Elly Martin

Elly Martin

Position: UKRI Future Leaders Fellow, Principal Research Fellow
Email: elly.martin@ucl.ac.uk
Phone: +44 (0) 20 7679 7992
Extension: 37992
Room: Malet Place Engineering Building, 3.18a
Address: Department of Medical Physics and Biomedical Engineering
University College London
Malet Place Engineering Building
Gower Street, London, WC1E 6BT
UCL Profile: https://profiles.ucl.ac.uk/47271-elly-martin

About

My research

I am a UKRI Future Leaders Fellow in the Department of Medical Physics and Biomedical Engineering and a WEISS Research Fellow at the Welcome EPSRC Centre for Interventional and Surgical Sciences at UCL. My research is mainly focused on the measurement and measurement based simulation of ultrasound fields, and ultrasonic device design and characterisation. These activities underpin the development of existing ultrasound therapies and new medical applications of ultrasound.

My current UKRI fellowship is focused on ultrasonic rewarming of biological cells and tissues after cryopreservation, with the aim of developing a flexible tool for uniform and rapid warming of increased volumes of material.

A particular focus of my work generally is concerned with making quantitative comparisons between accurate hydrophone measurements and simulations of acoustic fields made using the k-Wave acoustics toolbox. One current area of investigation is related to the modelling of the propagation of ultrasound through the skull for application in transcranial ultrasound therapies. I am also working on the development and characterisation of hardware for targeted ultrasonic neuromodulation in the deep brain as part of a multidisciplinary team.

I am a member of the British Standards Institute (BSI) Ultrasonics Technical Committee, and an expert member of 2 working groups of the IEC Ultrasonics Technical Committee TC87, as part of which I am currently working with a small team on a new international standard for measurement based ultrasound simulation.

I am also a member of the International Transcranial Ultrasonic Stimulation Safety and Standards (ITRUSST), an international consortium which brings together academics, clinicians, manufacturers, and regulatory bodies to work towards the safe and effective application of transcranial focused ultrasound for neuromodulation.

Career

Senior Research Fellow – WEISS Fellowship  2020 –
Wellcome/EPSRC Centre for Interventional & Surgical Sciences (WEISS)
Department of Medical Physics and Biomedical Engineering, University College London, UK


Postdoctoral Research Associate  2014 – 2020
Biomedical Ultrasound Group, Department of Medical Physics and Biomedical Engineering, University College London, UK


Higher Research Scientist  2011 – 2014
Ultrasonics, Acoustics Group, National Physical Laboratory, Teddington, UK


PhD Physics  2007 – 2010
Biomedical Physics Group, School of Physics, University of Exeter, Exeter, UK


Trainee Medical Physicist  2004 – 2006
University Hospitals Bristol NHS Trust, Bristol, UK


MSc Medical Physics (Pass with Merit)  2006
School of Physics, University of Exeter, Exeter, UK


MSci Physics with Astrophysics (1st class honours)  2004
School of Physics, University of Bristol, Bristol, UK

Journal Publications

1.

R. Xu; S. Bestmann; B. E. Treeby; E. Martin

Strategies and safety simulations for ultrasonic cervical spinal cord neuromodulation Journal Article

In: Physics in Medicine and Biology, 69 , pp. 125011, 2024.

Links | BibTeX

2.

E. Martin; J-F. Aubry; M. Schafer; L. Verhagen; B. E. Treeby; K. Butts Pauly

ITRUSST consensus on standardised reporting for transcranial ultrasound stimulation Journal Article

In: Brain Stimulation, 17 , pp. 607-615, 2024.

Links | BibTeX

3.

S. Liang; B. E. Treeby; E. Martin

Review of the Low-Temperature Acoustic Properties of Water, Aqueous Solutions, Lipids, and Soft Biological Tissues Journal Article

In: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 71 (5), pp. 607-620, 2024.

Links | BibTeX

4.

M. C. Klein-Flügge; E. F. Fouragan; E. Martin

The importance of acoustic output measurement and monitoring for the replicability of transcranial ultrasonic stimulation studies Journal Article

In: Brain Stimulation, 17 , pp. 32-34, 2023.

Links | BibTeX

5.

R. Xu; B. E. Treeby; E. Martin

Safety Review of Therapeutic Ultrasound for Spinal Cord Neuromodulation and Blood−Spinal Cord Barrier Opening Journal Article

In: Ultrasound in Medicine and Biology, 50 , pp. 317-331, 2023.

Links | BibTeX

6.

S. N. Yaakub; T. A. White; J. Roberts; E. Martin; L. Verhagen; C. J. Stagg; S. Hall; E. F. Fouragan

Transcranial focused ultrasound-mediated neurochemical and functional connectivity changes in deep cortical regions in humans Journal Article

In: Nature Communications, 14 , pp. 5318, 2023.

Links | BibTeX

7.

M. Roberts; E. Martin; M. D. Brown; B. T. Cox; B. E. Treeby

open-UST: An Open-Source Ultrasound Tomography Transducer Array System Journal Article

In: IEEE Transactions of Ultrasonics, Ferroelectrics, and Frequency Control, 70 (7), pp. 782-791, 2023.

Links | BibTeX

8.

E. A. Kipergil; E. Martin; S. J. Mathews; I. Papakonstantinou; E. J. Alles; A. E. Desjardins

Fiber-optic hydrophone for detection of high-intensity ultrasound waves Journal Article

In: Optics Letters, 48 (10), pp. 2615-2618, 2023.

Abstract | Links | BibTeX

9.

T. Nandi; A. Johnstone; E. Martin; C. Zich; R. Cooper; S. Bestmann; T. O. Bergmann; B. E. Treeby; C. J. Stagg

Ramped V1 transcranial ultrasonic stimulation modulates but does not evoke visual evoked potentials Journal Article

In: Brain Stimulation, 16 , pp. 553-555, 2023.

Links | BibTeX

10.

R. Xu; B. E. Treeby; E. Martin

Experiments and simulations demonstrating the rapid ultrasonic rewarming of frozen tissue cryovials Journal Article

In: J. Acoust. Soc. Am., 153 (1), pp. 517-528, 2023.

Links | BibTeX

11.

S. Singh; E. Martin; H. F. J. Tregidgo; B. E. Treeby; S. Bandula

Prostatic calcifications: Quantifying occurrence, radiodensity, and spatial distribution in prostate cancer patients Journal Article

In: Urologic Oncology: Seminars and Original Investigations, 39 (10), pp. 728.e1-e6, 2021.

Links | BibTeX

12.

A. Johnstone; T. Nandi; E. Martin; S. Bestmann; C. J. Stagg; B. E. Treeby

A range of pulses commonly used for human transcranial ultrasound stimulation are clearly audible Journal Article

In: Brain Stimulation, 14 (5), pp. P1353-1355, 2021.

Links | BibTeX

13.

E. Martin; M. Roberts; B. E. Treeby

Measurement and simulation of steered acoustic fields generated by a multielement array for therapeutic ultrasound Journal Article

In: JASA Express Lett., 2021.

Links | BibTeX

14.

E. Martin; J. Jaros; B. E. Treeby

Experimental validation of k-Wave: Nonlinear wave propagation in layered, absorbing fluid media Journal Article

In: IEEE Trans. Ultrason. Ferroelectr. Freq. Control, 67 (1), pp. 81-91, 2020.

Links | BibTeX

15.

B. E. Treeby; J. Jaros; E. Martin; B. T. Cox

From biology to bytes: Predicting the path of ultrasound waves through the human body Journal Article

In: Acoustics Today, 15 (2), pp. 36-44, 2019.

Links | BibTeX

16.

D. R. Ramasawmy; E. Martin; J. A. Guggenheim; E. Z. Zhang; P. C. Beard; B. E. Treeby; B. T. Cox

Analysis of the Directivity of Glass-Etalon Fabry-Perot Ultrasound Sensors Journal Article

In: IEEE Trans. Ultrason. Ferroelectr. Freq. Control, 66 (9), pp. 1504-1513, 2019.

Links | BibTeX

17.

E. Martin; B. E. Treeby

Investigation of the repeatability and reproducibility of hydrophone measurements of medical ultrasound fields Journal Article

In: J. Acoust. Soc. Am., 145 (3), pp. 1270-1282, 2019.

Links | BibTeX

18.

B. E. Treeby; F. Lucka; E. Martin; B. T. Cox

Equivalent-source acoustic holography for projecting measured ultrasound fields through complex media Journal Article

In: IEEE Trans. Ultrason. Ferroelectr. Freq. Control, 65 (10), pp. 1857-1864, 2018.

Links | BibTeX

19.

M. Bakaric; E. Martin; P. S. Georgiou; B. T. Cox; H. Payne; B. E. Treeby

Experimental study of beam distortion due to fiducial markers during salvage HIFU in the prostate Journal Article

In: Journal of Therapeutic Ultrasound, 6 (1), pp. 1-12, 2018.

Links | BibTeX

20.

E. Martin; E. Z. Zhang; J. A. Guggenheim; P. C. Beard; B. E. Treeby

Rapid spatial mapping of focused ultrasound fields using a planar Fabry-Perot sensor Journal Article

In: IEEE Trans. Ultrason. Ferroelectr. Freq. Control, 64 (11), pp. 1711-1722, 2017.

Links | BibTeX

21.

J. L. Robertson; E. Martin; B. T. Cox; B. E. Treeby

Sensitivity of simulated transcranial ultrasound fields to acoustic medium property maps Journal Article

In: Phys. Med. Biol., 62 (7), pp. 2559-2580, 2017.

Links | BibTeX

22.

E. Martin; Y. T. Ling; B. E. Treeby

Simulating focused ultrasound transducers using discrete sources on regular cartesian grids Journal Article

In: IEEE Trans. Ultrason. Ferroelectr. Freq. Control, 63 (10), pp. 1535–1542, 2016.

Links | BibTeX

23.

A. Shaw; E. Martin; J. Haller; G. ter Haar

Equipment, measurement and dose - a survey for therapeutic ultrasound Journal Article

In: J. Ther. Ultrasound, 4 , pp. 7, 2016.

Links | BibTeX

24.

E. Martin; A. Shaw; C. Lees

Survey of current practice in clinical transvaginal ultrasound scanning in the UK Journal Article

In: Ultrasound, 23 (3), pp. 138–148, 2015.

Links | BibTeX

25.

V. A. Khokhlova; S. M. Shmeleva; L. R. Gavrilov; E. Martin; N. Sadhoo; A. Shaw

Infrared mapping of ultrasound fields generated by medical transducers: Feasibility of determining absolute intensity levels Journal Article

In: J. Acoust. Soc. Am., 134 (2), pp. 1586–1597, 2013.

Links | BibTeX

26.

J. Haller; K.-V. Jenderka; F. Seifert; T. Klepsch; E. Martin; A. Shaw; G. Durando; C. Guglielmone; F. Girard

A comparison of three different types of temperature measurement in HITU fields Journal Article

In: Metrologia, 49 (5), pp. S279–S281, 2012.

Links | BibTeX

27.

E. Martin; F. A. Duck; C. P. Winlove

Thermally-mediated ultrasound-induced contraction of equine muscular arteries in vitro and an investigation of the associated cellular mechanisms Journal Article

In: Ultrasound Med. Biol., 38 (1), pp. 152–161, 2012.

Links | BibTeX

28.

E. Martin; F. A. Duck; R. E. Ellis; C. P. Winlove

Ultrasound-induced contraction of the carotid artery in vitro Journal Article

In: Ultrasound Med. Biol., 36 (1), pp. 166–172, 2010.

Links | BibTeX

29.

E. Martin

The cellular bioeffects of low intensity ultrasound Journal Article

In: Ultrasound, 17 (4), pp. 214–219 , 2009.

Links | BibTeX

Conference Publications

1.

R. Xu; T. Brookshaw; E. Erro; M. Roberts; C. Selden; E. Martin

Device Design for the Rapid Ultrasonic Rewarming of Alginate Beads and Cryoprotectant Solution to Improve Cryopreservation Recovery Conference

2024 IEEE International Ultrasonics Symposium (IUS)., 2024.

Abstract | Links | BibTeX

2.

M. Roberts; E. Martin; M. D. Brown; B. T. Cox; B. E. Treeby

Matching Layer Deposition for an Open-Source Ultrasound Tomography System: Inter-Element Variation in Frequency Response Conference

2022 IEEE International Ultrasonics Symposium (IUS), 2022.

Links | BibTeX

3.

M. Roberts; E. Martin; M. D. Brown; B. T. Cox; B. E. Treeby

Transducer Module Development for an Open-Source Ultrasound Tomography System Conference

2021 IEEE International Ultrasonics Symposium (IUS), 2021.

Links | BibTeX

4.

E. Martin; A. Hurrell; J. Choi; B. E. Treeby

Quantifying the effects of standing waves within the skull for ultrasound mediated opening of the blood-brain-barrier Conference

2021 IEEE International Ultrasonics Symposium (IUS), 2021.

Links | BibTeX

5.

M. Roberts; E. Martin; B. T. Cox; B. E. Treeby

Progress towards an open-source, low-cost ultrasound computed tomography research system Conference

The 2nd International Workshop on Medical Ultrasound Tomography (MUST 2019), KIT Press, 2019.

Links | BibTeX

6.

L. Albelda Gimeno; E. Martin; O. Wright; B. E. Treeby

Experimental assessment of skull aberration and transmission loss at 270 kHz for focused ultrasound stimulation of the primary visual cortex Conference

IEEE International Ultrasonics Symposium, 2019.

Links | BibTeX

7.

D. R. Ramasawmy; E. Martin; J. A. Guggenheim; B. T. Cox; B. E. Treeby

Directivity of a planar hard-dielectric Fabry-Perot optical ultrasound sensor Conference

IEEE International Ultrasonics Symposium, 2017.

Links | BibTeX

8.

M. D. Brown; E. Martin; B. T. Cox; B. E. Treeby

Single pulse illumination of multi-layer photoacoustic holograms for patterned ultrasound field generation Conference

IEEE International Ultrasonics Symposium, 2016.

Links | BibTeX

9.

E. Martin; E. Z. Zhang; P. C. Beard; B. E. Treeby

Rapid spatial mapping of the acoustic pressure in high intensity focused ultrasound fields at clinical intensities using a novel planar Fabry-Perot interferometer Conference

IEEE International Ultrasonics Symposium, 2015.

Links | BibTeX

10.

Y. T. Ling; E. Martin; B. E. Treeby

Discrete source model for simulating bowl-shaped focused ultrasound transducers on regular grids: Design and experimental validation Conference

IEEE International Ultrasonics Symposium, 2015.

Links | BibTeX

11.

E. Martin; B. E. Treeby

Experimental validation of computational models for large-scale nonlinear ultrasound simulations in heterogeneous, absorbing fluid media Conference

International Symposium on Nonlinear Acoustics (AIP Conference Proceedings), 1685 , 2015.

Links | BibTeX

12.

G. Durando; C. Guglielmone; J. Haller; O. Georg; A. Shaw; E. Martin; B. Karaboce

Towards comparison of ultrasound dose measurements - current capabilities and open challenges Conference

Proceedings of the 2015 ICU International Congress on Ultrasonics, 70 , 2015.

Links | BibTeX

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